In MLA style, should an ampersand in a publisher’s name be changed to and?

Note: This post relates to content in the eighth edition of the MLA Handbook. For up-to-date guidance, see the ninth edition of the MLA Handbook.

Yes. Just as you would change an ampersand in a title to and, change an ampersand to and in a publisher’s name in your prose and in your works-cited list:

In your source: Farrar & Rinehart

In your paper:  Farrar and Rinehart